promotion qualify of Pharmaceutical grade purchase 25655-41-8 Povidone Iodine (PVP-I)
KoVidone® - I
Product name KoVidone® - I
USP name Povidone - Iodine
EP name Povidone Iodinated (Povidonum Iodinatum)
INCI/CTFA PVP-Iodine
CAS NO. 25655-41-8
Product Name: |
Povidone iodine |
Synonyms: |
disadined.p.;disphex;efo-dine;inadine;iodine-polyvinylpyrrolidonecomplex;poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodinecomplex;polyvinyl;Povidone iodine/povidone-iodine solution |
CAS: |
25655-41-8 |
MF: |
C8H15NO |
MW: |
141.2108 |
EINECS: |
607-771-8 |
Product Categories: |
Polymers;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;disinfectant;-;Iodine bactericidal action |
Mol File: |
25655-41-8.mol |
|
Properties Broad spectrum biocide; Soluble in water, ethyl alcohol, isopropyl alcohol, glycols, glycerin, acetone and polyethylene glycol; Film-forming; Stable complex; Less irritating to the skin and mucosa; Non-selective germicidal action; No known tendency for the development of resistant microorganisms.
Effective Iodine 9.0-12.0 %
Applications
KoVidone® -I is a broad spectrum biocidal, antifungal and antiviral agent with extremely low risk of promoting microorganism resistance. Applications include:
• Used as an antiseptic agent against abroad spectrum of disease causing microorganisms.
• Widely used in pharmaceutical, veterinarian, agricultural and consumer good applications.
• Used for the disinfecting of skin and equipment before injection or surgery.
• Used for the treatment of: oral, vaginal, skin and hair infections.
• Highly effective at inactivating human and avian influenza viruses.
• Disinfectant used in the foodstuff, aquaculture and veterinarian industries to control pathogenic bacteria, reduce the infection of fish and fish eggs and prevent and cure animal diseases.
Broad specturm biocide; soluble in water, ethyl alcohol; isopropyl alcohol; glycols, glycerin, acetone and polyethylene glycol.Film-foming; stable complex; less irritating to the skin an mucosa.
Povidone iodine Usage And Synthesis
Topical disinfectants Povidone iodine is an unstable complex formed from the complexation of iodine with a surfactant, belonging to a type of topical iodine disinfectant. At room temperature, it is yellow-brown to red-brown amorphous powder which is soluble in water or ethanol but insoluble in ether or chloroform. Thevinyl-2-pyrrolidone homopolymer inside it is a kind of surfactants which can facilitate the wetting and penetration of solution on the object, thereby enhancing the sterilization effect of iodine. Of which 80 to 90% of the binding iodine can be depolymerization into free iodine with a large the concentration and a strong bactericidal capability. It is tasteless, non-irritating, non-allergenic, and of low toxicity. It is a kind of broad-spectrum fungicide which can kill viruses, bacteria, spores, fungi, and protozoa. At a concentration of 15ppm, within 1 minute, it can kill various kinds of bacteria (Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa) propagules; it takes a relative long time for it to kill Mycobacterium tuberculosis; killing fungi (B. subtilis) takes 1.5 hours; killing black variant of Bacillus cereus and Bacillus requires higher concentrations and longer time; at a concentration of 150ppm, within 10 minutes, it can destroy the hepatitis B surface antigen (HBsAg). In addition to be applied for the skin disinfection, this product can also be used for disinfecting of metallic medical equipment, utensils and the like. It is usually read or amber in the concentration for disinfection which can not only be directly applied to the skin or meninges of the surgical incision site of a patient, but also used for the in vitro flushing purposes in obstetrics and urology. When its concentration is reduced to below 10ppm, it turns white or pale yellow and loses bactericidal activity.